Hello, I'm Ed / Yoshi (he/him).
I am a research and development (R&D) engineer specializing in developing deep learning tools for virtual staining
and segmentation of dynamic cell systems at the Chan Zuckerberg Biohub SF.
My expertise lies in integrating advanced computer vision models with imaging systems to enable smart microscopy,
such as tools that facilitate the tracking and perturbation of dynamic organ systems in model organisms, such as zebrafish.
I earned my Ph.D. from the Jack Baskin School of Engineering,
UC Santa Cruz, in 2022. During my Ph.D., I developed a fast, live 3D imaging multi-focus microscope using a 25-camera array with Dr. Sara Abrahamsson.
I completed my B.S. in Bioengineering in 2018 at UC Santa Cruz.
Gallery
Virtual staining OpenCell targets
C.elegans GCaMP expression captured with the M25
News
- 2025-06-23 - Updated our preprint on "DynaCLR: Contrastive Learning of Cellular Dynamics with Temporal Regularization" adding knowledge distillation and pseudotime alignment here .
- 2025-06-23 - Our "Robust virtual staining of landmark organelles with Cytoland" is now available on Nature Machine Intelligence here .
- 2025-03-20 - Our paper "Mapping virus infection dynamics across scales with computational imaging" published in High-Throughput Biophotonics: Imaging, Spectroscopy, and Beyond X here .
- 2025-03-20 - Our paper "3D computational imaging of dry mass and orientation" published in Quantitative Phase Imaging XI here .
- 2025-01-31 - Presented applications of virtual staining in zebrafish neuromast titled "Mapping cell state dynamics with AI-enabled live cell imaging" at Photonics West 2025, High-throughput Biophotonics session. here .
- 2024-09-23 - Our preprint on High-speed 3D Imaging with 25-Camera Multifocus Microscope here .
- 2024-09-20 - Our demo for 2D Virtual Staining is now up on HuggingFace here .
- 2024-09-03 - Our paper "Ultrack: pushing the limits of cell tracking across biological scales" published in bioRxiv here .
- 2024-08-20 - I'll be teaching the image-translation section at the DL@MBL course. Checkout the exercise if you are interested here
- 2024-08-09 - Our work on high-throughput 4D imaging and analysis is up in PNAS Nexus here .
- 2024-07-01 - Our paper "High Throughput Imaging and Analysis of Intracellular Dynamics with Correlative Label-Free and Fluorescence Microscopy" published in Microscopy and Microanalysis here .
- 2024-06-03 - Our preprint on robust virtual staining of landmark organelles is online bioRxiv .
- 2024-01-01 - Our paper "waveOrder: generalist framework for label-agnostic computational microscopy" published in arXiv.org here .
- 2023-12-19 - Our preprint on high-throughput 4D imaging and analysis of the molecular and physical architecture of cells is online bioRxiv .
- 2023-09-19 - Moved to the peninsula to join the Computational Microscopy Platform at the Chan Zuckerberg Biohub San Francisco as R&D Engineer.
- 2022-08-22 - Successfully defended my dissertation at the Jack Baskin School of Engineering, University of California Santa Cruz.
- 2022-03-11 - Our work on fast volumetric multifocus structured illumination microscopy is online in Biomedical Optics Express here .
- 2022-01-01 - Our paper "Image Reconstruction for live 3D Multifocus Super-Resolution Microscopy" published in Imaging and Applied Optics Congress 2022 (3D, AOA, COSI, ISA, pcAOP) here .
- 2022-01-01 - Our paper "Ultrafast Live 3D Imaging with 25-plane Camera Array Multifocus Microscopy" published in Imaging and Applied Optics Congress 2022 (3D, AOA, COSI, ISA, pcAOP) here .
- 2020-05-01 - Our paper "Camera-Array 25-Plane Multifocus Microscope for Ultrafast Live 3D Imaging" published in Conference on Lasers and Electro-Optics here .
- 2020-03-09 - Our paper "25 plane multifocus microscopy for fast and live 3D imaging (Conference Presentation)" is available here .
- 2019-09-20 - Awarded the Fall 2019 travel award to present my work at the "Seeing is Believing: Imaging the Molecular Processes of Life" in Heidelberg, Germany.
- 2019-02-01 - Our paper "Simultaneous 25 Plane 3D Live Imaging System for Neural Circuits" published in Biophysical Journal here .
- 2018-06-26 - Starting my Ph.D. in the Electrical and Computer Engineering department at UCSC with Sara Abrahamsson SaraLab developing fast and aberration-free multi-focus microscopes.
- 2018-05-20 - Awarded the 2018 Dean's Award for our "Automatized Surface Functionalization for Diagnostic Systems" project with the Yanik Group.
- 2016-03-15 - Awarded the 2016 Sara Matthews Award from UC Santa Cruz for scholarly excellence and campus involvement.
- 2014-09-01 - Moved to the U.S. to pursue my B.S. in Bioengineering at the Jack Baskin School of Engineering at the University of California Santa Cruz.